The "49ers Postgame Live" crew highlights George Kittle's play in San Francisco's 41-22 win over the Arizona Cardinals on Sunday at State Farm Stadium.49ers star George Kittle reaches TD milestone with two-score game vs.

Christian McCaffrey National Football League San Francisco 49ers Top Plays NFL - San Francisco 49ers vs. Arizona Cardinals - 11/16/2025

In a battle of 7-2 teams, it was the Rams who survived a heavyweight showdown in the NFC West. The Seahawks have no one to blame but themselves, as Sam Darnold threw four interceptions in the loss. Los Angeles now has the inside track to win the division, but these teams will go head-to-head again in Week 16 on "Thursday Night Football."

The "49ers Postgame Live" crew highlights running back Christian McCaffrey after San Francisco's 41-22 win over the Arizona Cardinals on Sunday.Christian McCaffrey totals 121 yards, three TDs in 49ers' big win vs.

Brock Purdy hit George Kittle for 30-yard TD, extending the San Francisco 49ers lead over the Arizona Cardinals.

SANTA CLARA, Calif. — San Francisco 49ers quarterback Brock Purdy was set to have an “aggressive” practice on Wednesday and the goal this week is for him to start a game for the first time since reinjuring his toe in Week 4.

The Arizona Cardinals‘ attempt to rebound from a divisional blowout was unsuccessful on Sunday, as they were dominated by the San Francisco 49ers to the tune of a 41-16

Matt Maiocco highlights five key 49ers to keep an eye on in San Francisco's pivotal Week 11 matchup against the Arizona Cardinals on Sunday.