Highlights from the Week 11 matchup between the San Francisco 49ers and the Arizona Cardinals during the 2025 NFL season.

Kickoff from State Farm Stadium is set for 4:25 p.m. ET on FOX. The 49ers are 3.5-point favorites, according to the latest 49ers vs. Cardinals odds. The over/under for total points scored is 48.5. Before making any 49ers vs. Cardinals picks, make sure you check out the NFL picks from the SportsLine Projection Model.

A big stretch of games begins for the San Francisco 49ers on Sunday in Arizona against the Cardinals. Here's how to watch their Week 11 showdown.

Arizona had the passing game working, but it didn't matter in a 41-22 loss to San Francisco at State Farm Stadium in Glendale.

The Arizona Cardinals are back in action in Week 11, facing the San Francisco 49ers for the second time this season. The 6-4 49ers and 3-6 Cardinals kick off from State Farm Stadium in Glendale, Arizona at 4:05 p.m. ET (2:05 p.m. Arizona time).

USA Today's NFL experts make their picks for a Week 11 showdown between the Arizona Cardinals and San Francisco 49ers

The San Francisco 49ers dominated their Week 11 matchup as the Arizona Cardinals were exposed once again.

The San Francisco 49ers and Arizona Cardinals face off in Week 11 of the NFL today. Here's where to watch and start time

Learn which TV channel or how to live stream the NFL Week 11 Arizona Cardinals and San Francisco 49ers game, Sunday, Nov. 16.

Arizona Cardinals vs San Francisco 49ers picks, predictions, odds, win probabilities for NFL Week 11 Sunday game on Nov. 16. Who will win game today?