This important study reveals that mitotic release of an ER-microtubule tether is critical for normal mitotic progression. Manipulating CLIMP63 phosphorylation, the authors provide convincing evidence ...

Cells can measure how long they spend in mitosis. If mitosis is prolonged due to problems during chromosome separation, the Mitotic Stopwatch Complex is formed, which may lead to cell arrest or cell ...

Researchers have found a molecular mechanism that prevents multiplication of potentially dangerous cells by measuring the duration of mitosis. They have shown that this mechanism -- the Mitotic ...