Background The association of Modic changes (MC) with low back pain (LBP) is unclear. The purpose of our study was to investigate the associations between the extent of Type 1 (M1) and Type 2 (M2) MC ...
Modic changes are radiographic features associated with microfracture, low-virulence organism infection and chronic inflammation with inflammatory cell infiltration in the vertebral endplate region.
In this 2-year follow-up study, we found a significant positive association between the change in the extent of M1 and change in ODI. We also found a positive association between the change in the ...
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