National Institutes of Health researchers have identified a compound called N-desethyl-fluornitrazene, or DFNZ, that ...

Using a long-abandoned class of opioids as their starting point, scientists have discovered an opioid painkiller that doesn't ...

Opioids such as morphine, oxycodone and fentanyl provide pain relief by binding to mu-opioid receptors, which are specialized ...

More good news in the battle against opioid addiction. Scientists have reopened research into a class of opioids that were ...

Tiger Woods allegedly had two hydrocodone pills in his left pants pocket when he flipped his Land Rover and was subsequently ...

Opioid drugs are highly effective at relieving pain but come with severe drawbacks. Their side effects range from dizziness to potentially fatal respiratory depression. Their illegal use contributes ...

Scientists have developed a new gene therapy that quiets pain at its source in the brain—without the addictive risks of opioids. Using AI to map how pain is processed, they created a targeted “off ...

An experimental drug developed at Duke University School of Medicine could offer powerful pain relief without the dangerous side effects of opioids. The drug, called SBI-810, is part of a new ...

Previously shown to deliver morphine-comparable pain relief without opioid-related risks in a validated inflammatory pain model, supporting planned IND submission for inflammatory pain ...

Research shows that patients who receive nerve blocks for musculoskeletal surgery often take less pain medication, not only ...

One year after FDA approval, Journavx (suzetrigine) offers a promising non-opioid option for acute pain, but experts have ...

Naltrexone is a generic prescription drug used to treat certain substance use disorders. Naltrexone oral tablet does not come in any brand-name versions. This drug can cause mild to serious side ...