Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for ...
The gene p53 acts as a tumor suppressor and often is called the ‘guardian of the genome.’ This gene is central to maintaining genomic stability, which prevents mutations from accumulating and leading ...
Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for therapeutics. Among them, the Y220C mutation is the ninth most frequent and it ...
The discovery could pave the way for new treatments, improved risk prediction, and earlier intervention for brain metastases.
A new hypothesis article was published in Oncotarget (Volume 17) on January 3, 2026, titled “Hypothesis: HPV E6 and COVID ...
Researchers have uncovered a mechanism that allows breast cancer to send metastases to the brain, potentially enabling the ...
Loss of a chromosome 17 segment disables the p53 gene, helping breast cancer cells survive and grow in the brain’s environment.The post Israeli team uncovers how breast cancer spreads to ...
From new imaging and targeted therapies to patient journeys, 2025 highlighted key advances and personal stories in lung ...
A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the ...
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