Post-translational modifications (PTMs) play a key role in dynamic cellular processes, regulating gene expression, protein activity, localization, and degradation, as well as protein interaction.
The focus of vertebrate studies has mainly been on canonical phosphorylation, but research indicates that phosphorylation of other non-canonical amino acids also regulates integral aspects of cell ...
The amino acid side chains of proteins undergo various post-translational modifications (PTMs) which significantly impact protein function and mediate complex cellular events. Measuring the dynamics, ...
Unlike bacteria or yeast, moss can produce large polypeptides of human collagen along with the post-translational modifications that make it stable and bioactive.
Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...
Post-translational modifications (PTMs)—the chemical changes that proteins undergo following biosynthesis—account for most protein forms, or proteoforms. Indeed, according to conservative estimates, ...
Being bullied leaves a biochemical footprint in the brain. Protein lactylation is a very recently discovered post-translational modification of protein that involves the addition of a lactyl group to ...
A worldwide study involving 12 research groups has confirmed that capillary zone electrophoresis combined with mass ...
Researchers discovered a novel protein modification driven by IDH mutations that alters cancer metabolism. The build-up of ...
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