For more than two decades, the International Space Station has provided a platform for growing and studying protein crystals. In the early days of microgravity research, scientists discovered that ...

A quick, purification-free method was developed by researchers at the Institute of Science Tokyo, to capture the detailed 3D structures of flexible sugar molecules. By growing crystals of galectin-10 ...

The problem of protein structure determination is usually solved by X-ray crystallography. Several in silico deep learning methods have been developed to overcome the ...

Correlative cryo-light microscopy and cryo-FIB workflows improve the localization and preparation of intracellular crystals ...

Advances in structural biology have allowed scientists to determine molecular structures with atomic-level detail, sometimes yielding static snapshots that do not reflect the dynamism of proteins.

Serial crystallography (SX) has revolutionized structural biology by enabling high-resolution structure determination for important classes of proteins, including the study of relevant biomolecular ...

Fluidigm's TOPAZ 1.96 screening chips employ microscale channels and valves for diffusive mixing of protein and crystallization reagents. Future chip designs will steadily increase parallel throughput ...

Within biopharmaceutical companies, crystallography is generally the purview of research scientists involved in structure-based drug design. Its potential for protein purification has been known for ...

The proposed strategy can help achieve a better understanding of protein structures and interactions, paving the way to advances in biology and medicine. Intrinsically disordered proteins (IDPs) can ...

Dr. Lynch is a quantitative and computational scientist focused on applications in structural biology and image analysis. Her work focuses on how we can use imaging methods to better detect and ...

Our facility supports production and purification of high quantity and purity protein samples. We have instrumentation for the growth, cell harvesting, and lysis of large volume bacterial and insect ...