Ligand binding to membrane proteins is critical for many biological signaling processes. However, individual binding events are rarely directly observed, and their asynchronous dynamics are occluded ...
RNA-binding proteins (RBPs) are critical regulators of gene expression and RNA processing that are required for gene function. Yet the dynamics of RBP regulation in single cells is unknown. To address ...
Mapping transcription factor (TF) binding sites across the genome is key to understanding how cells control gene expression, yet pinpointing their footprints across the genome—especially in single ...
SPRm (Surface Plasmon Resonance Microscopy) is a novel technology that enables label-free and real-time binding affinity and kinetics of membrane proteins with drug molecules. By combining cell ...
LA JOLLA, CA—A new study led by scientists at La Jolla Institute for Immunology (LJI) shows how ideal antibodies against SARS-CoV-2 hit their marks. That's right: marks. Instead of targeting a single ...
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