Granulomas are cellular aggregates that are the pathologic hallmarks of tuberculosis. These chronic inflammatory lesions have long been considered to be necessary for containment of infection. A ...

The pathogen Mycobacterium tuberculosis (Mtb) has evolved to cause infection in many, but active disease in few. The World Health Organization estimates that one third of the planet's population ...

An Asian woman who immigrated to this country was diagnosed with miliary pulmonary TB per lung biopsy that showed a caseating granuloma. Both her purified protein derivative test and sputum culture ...

One of the main challenges for tuberculosis (TB) therapy is how to deliver drugs to the site of disease. Once the body’s immune system is infected with tuberculosis, it forms granulomas—tight clusters ...