What is the recommended approach to managing a patient infected with hepatitis C virus who has been on combination interferon and ribavirin therapy and who has developed peripheral neuropathy?

Demyelinating features were more profound suggesting a demyelinating polyneuropathy with secondary axonal changes.

When laboratory tests cannot determine the cause, the condition is known as chronic idiopathic axonal polyneuropathy; a cause is eventually found in only 7 to 30 percent of these cases.

Changes in axonal excitability may be useful as an early biomarker of disease progression that could guide treatment in patients with ATTRv-PN.

Small tumor-like overgrowths of axons, termed axonomas, were found in the central and peripheral nervous system, indicating attempted axonal regeneration.

Eight patients (62%) were given a clinical diagnosis of axonal polyneuropathy, two (15%) showed evidence of spinal cord degeneration, and three (23%) showed clinical symptoms of both ...

Chronic inflammatory demyelinating polyneuropathy (CIDP) diagnoses are frequently missed or delayed and standard treatments -- intravenous immunoglobulin (IVIG), steroids, and plasma exchange ...

Disarm Therapeutics announces preclinical data demonstrating that small molecule inhibitors of SARM1 protect axons in models of axonal degeneration.

Although significantly increased in subjects with new diabetes, the rates of typical diabetic polyneuropathy (DPN), retinopathy, and nephropathy are not significantly different between subjects ...

Disarm Therapeutics announces the first subject enrolled in the Chemotherapy-Induced Peripheral Neuropathy Natural History Study.