ActA mediates cross-talk between breast cancer cells and cancer-associated fibroblasts in the lung metastatic niche that enhances fibrosis and metastasis, implicating ActA as a potential therapeutic ...

Mesothelin secretion by cancer cells supports pancreatic cancer metastasis by inducing macrophage secretion of VEGFA and S100A9 to support cancer cell proliferation and survival, recruit neutrophils, ...

1Pancreas Center, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, State Key Laboratory of Druggability Evaluation and Systematic Translational ...

Cancer Discov (2026) 16 (1): OF1.

3Department of Biology, Stanford University, Stanford, California. 5Cancer Biology Program, Stanford University School of Medicine, Stanford, California. 12Chan Zuckerberg Biohub, San Francisco, ...

In MTAP-deficient cancer cells, PRMT5 expression and activity is preferentially required for cell growth. Major finding: In MTAP-deficient cancer cells, PRMT5 expression and activity is preferentially ...

Abstract. AZD9833 is a potent, orally delivered, non-steroidal selective estrogen receptor degrader (SERD) that both antagonizes and degrades ERα. It is currently in clinical testing for the treatment ...

1Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California. 2Cancer Institute, Stanford University School of Medicine, Stanford, ...

1Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, NCI, NIH, Bethesda, Maryland. *Corresponding Author: Cari M. Kitahara, Division of ...

1Adult Stem Cell Research Center and Research Institute for Veterinary Science, Seoul, Republic of Korea.

1Laboratory of Rare Human Circulating Cells (LCCRH), University Medical Centre of Montpellier, Montpellier, France.

Mitochondrial glutathione import via SLC25A39 supports breast cancer metastasis by linking glutathione availability to ATF4-driven integrated stress response signaling during early metastatic ...