Peptide inhibitors of E3 ubiquitin ligase anaphase-promoting complex/cyclosome, engineered for enhanced affinity by incorporating unnatural amino acids, are able to block substrate ubiquitination and ...

DNA aptamers are powerful molecular tools in biosensing, bioimaging and therapeutics. However, a limited understanding of ...

Myristoylation is a co-translational process catalyzed by N-myristoyltransferases (NMTs) on ribosomes, but its mechanism ...

Here, we define a requirement for neural activity in mobilizing the antioxidant defenses of the nematode Caenorhabditis elegans both during chronic oxidative stress and prior to its onset. We show ...

Homoplasmic mitochondrial mutations will be transmitted to all maternal offspring; however, due to the complex interplay between the mitochondrial and nuclear genomes, it is often difficult to ...

Food web is an important conceptual tool for illustrating the feeding relationships among species within a community, revealing species interactions and community structure, and understanding the ...