Thairo Estrada hit a two-run homer in the first inning and drove in four runs to help the Colorado Rockies beat the Houston Astros 7-6 on Thursday.

Estrada, who boosted his average to .317, went 3 for 4. He tied the game, 2-2, with a two-run homer to left off Astros left-hander Brandon Walter in the first. Estrada’s infield grounder scored Kyle Farmer to put Colorado in front, 3-2, in the third.

The loss was just the fifth in the past 21 games for the Astros, who had won the first two games of the series.

The Astros are heavily favored (-286 on the moneyline) when they square off against the Rockies (+230). The Houston Astros will give the start to Brandon Walter (1-1, 3.34 ERA), who is looking for win No.