The Big 12 released its 2025 football schedule Tuesday, setting the stage for another season of back-and-forth battles in a conference that delivered thrills on a weekly basis in 2024. When Big 12 commissioner Brett Yormark banged the podium to proclaim his conference the most competitive in the country at media days last July,

The 2024 college football season featured dozens of highly entertaining games. But the Arizona State vs. Texas matchup in the College Football Playoff quarterfinals arguably topped them all. The game featured everything.

Week 1 of the 2025 college football season features a loaded slate, including LSU at Clemson, Notre Dame at Miami and Alabama at Florida State, among others. LSU-Clemson could be a top-five matchup, as could the biggest headliner: Manning and Texas visiting Ohio State in a matchup of the 2024 national champion and our early 2025 favorite.

Notre Dame is fresh off an impressive run to the College Football Playoff National Championship, taking full advantage of the first year of the 12-team format while marching to Atlanta as the No. 7 seed.

Big 12 football schedule has some very big games on it. Here are 12 of the biggest, including Arizona State vs Iowa State, BYU vs Colorado.