After being informed of a potential microduplication in Figure 1D, the journal contacted the authors for clarification. The ...

Plants produce a wide diversity of compounds. Broadly, these are separated into primary metabolites, which are necessary for ...

Although the Arabidopsis thaliana RPD3-type histone deacetylase HDA19 and its close homolog HDA6 participate in SIN3-type histone deacetylase complexes, they display distinct biological roles, with ...

Uncoupling protein 1 (UCP1, SLC25A7) is responsible for the thermogenic properties of brown adipose tissue. Upon fatty acid activation, UCP1 facilitates proton leakage, dissipating the mitochondrial ...

(A) Results of DNA microarray datasets analyzing brown adipose tissue (BAT) from adipose tissue-specific Vegfa knockout mice (Adipo- Vegfa KO) (GSE221854) or high-fat diet (HFD) fed wild-type mice ...

N6-methyladenosine (m 6 A) exerts many of its regulatory effects on eukaryotic mRNAs by recruiting cytoplasmic YT521-B homology-domain family (YTHDF) proteins. Here, we show that in Arabidopsis ...

Arthritis was induced in mice exposed to high blood levels of homocysteine. Hyper-homocysteinemia arthritic animals develop diastolic dysfunction (the left ventricle does not dilate properly) with ...

Corneal diseases can cause severe visual impairment and even blindness, which have been linked to the interruption of corneal epithelial homeostasis. However, the underlying molecular mechanisms are ...

MCM8 deficiency impairs meiotic homologous recombination repair, but the specific role of MCM8 in mitotic germ cells remains poorly understood. This study reveals that MCM8 interacts with helicase ...

Import and assembly of mitochondrial proteins into multimeric complexes are essential for cellular function. Yet, many steps of these processes and the proteins involved remain unknown. Here, we ...

Motile cells can use and switch between different modes of migration. Here, we use traction force microscopy and fluorescent labeling of actin and myosin to quantify and correlate traction force ...

Prostate cancer (PCa) is the second most frequently occurring cancer and the fifth leading cause of cancer mortality among men worldwide in 2022 (Bray et al, 2024). Androgen receptor (AR) is ...