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Medicine Mondays: Cushing’s Disease, Part 2 Now that we’ve talked about how to diagnose Cushing’s, Part 2 is all about differentiating the two main forms. Most dogs have pituitary-dependent Cushing’s, where a pituitary tumor overstimulates both adrenal glands. A smaller percentage have adrenal-dependent disease, caused by a cortisol-secreting adrenal tumor acting independently. In this video, I walk through how we tell the difference using hormone testing patterns, endogenous ACTH, and imaging,
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